Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p47 | Bone development/growth and fracture repair | ECTS2016

Bone-forming ability of recombinant human bone morphogenetic protein 2 after repeated administration in mice

Koh Jeong-Tae , Kim Yuri , Son Hye-Ju , Hwang Yun-Chan , Ryu Je-Hwang

Delivery of recombinant human bone morphogenetic protein (rhBMP2) with various carriers has been showing the successful induction of bone formation in many bony defects, including oral and maxillofacial regions. However, effectiveness of the exogenous proteins, when repeatedly administered into different regions in an individual, has not been determined. The present study was aimed to examine alterations of ectopic or orthotopic bone generation and serum level of anti-BMP2 ant...